Experiment Readiness

Will it detect the gene that matters?

Score whether a planned experiment can detect a single gene of a given effect size, before you spend the money. This checks your design, not your hypothesis.

Start from a preset

Fold change of the gene you need

The effect of the gene that matters. 2 = a doubling; a strong knockdown is often 4 or more.

Sample type (variability)

Sets biological CV, the biggest driver of power.

Biological replicates / group

Independent samples, not technical reps.

Genes searched

20,000 = genome-wide screen (FDR control; the exact count does not change per-gene power). 1 = validating a single pre-specified gene.

Conditions randomized across batches(uncheck to simulate a confounded design)